Advancements in bio therapeutics and drug delivery

Biotherapeutic drug delivery system uses drug molecules made prepared from living organism naturally or in the laboratory. Fusion proteins, antibodies and therapeutic replacement enzymes are the major used bio therapeutic agents. Human insulin is the first bio therapeutic drug developed by recombinant-DNA technology and was approved by Eli Lily. These drugs have bought boom in the treatment of cancer, autoimmune disease, inflammatory diseases, haemophilia, cardio vascular disease and some genetic disorders. These drugs are differentiated as non-immune proteins, peptides and small therapeutic proteins and therapeutic antibodies and Fc- like fusion proteins. These bio therapeutic drugs act by different mechanism of actions like direct enzyme replacement, effector functions, cytokine and growth factor blockage, receptor blockage and modulation, toxin conjugation, stimulation of biological signal responses or by an enzyme inhibition. Hybridomas, human antibodies from mice, chimerization, humanization, glycoengineering and intrbodies are some carriers used in this drug delivery system.


  • Biotherapeutics generation Tools
  • Safety and side effects of biotherapeutics
  • Focused Ultra sound (FUS) technology
  • Transcranial Brain Drug Delivery
  • Intranasal Delivery
  • Endocytosis and Transcytosis (Adsorptive and Receptor Mediated)
  • Chemical Delivery Systems

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